A Study of Meaning-Centered Therapy for Mexican Adults With Advanced Cancer

Clinicaltrials.gov ID: NCT07225309
db-list-check Status RECRUITING
b-loader Phase NA
b-people Age ≥ 18 Years
b-bullseye-arrow Enrollments 300

Conditions

Breast Cancer, Prostate Cancer, Colorectal Cancer, Thyroid Cancer, Breast Cancer Stage III, Breast Cancer Stage IV, Prostate Cancer Stage III, Prostate Cancer Stage IV, Colorectal Cancer Stage III, Colorectal Cancer Stage IV, Thyroid Cancer Stage III, Thyroid Cancer Stage IV

Summary

The purpose of this study is to find out if Meaning-Centered Psychotherapy for Latinos (MCP-L) helps reduce anxiety and depression and improves quality of life compared to cognitive behavioral therapy (CBT). Investigators also want to learn what participants and providers think about the therapy, including how the therapy is designed, outside factors, available resources, and how the people involved affect how well MCP-L works.

Locations

1 location Found with status Recruiting

Status

  • RECRUITING

Contact Person

  • Devika Jutagir, PhD
  • 646-888-8361

Principal Investigator

  • Devika Jutagir, PhD

Eligibility Criteria

Patient Eligibility Criteria:

A patient cannot be considered eligible for this study unless ALL of the following conditions are met. Participant eligibility will be determined by an initial EMR review followed by a self-report screener and suicide risk assessment.

Inclusion Criteria:

EMR Criteria

- Documentation of Disease

* Pathologically confirmed breast, prostate, colorectal, thyroid, cervix, uteri, or lung - solid tumor cancer (either most recent or new diagnosis)

* Definition of Disease [or Measurable Disease]
* Diagnosed with stages III or IV

* Prior Treatment
* Receiving ambulatory care at INCan

Self-Report Criteria

* Age ≥ 18 years
* Able to read and communicate in Spanish determined by the question: "Can you read and communicate in Spanish? Yes/No"
* Professional role of administrators, clinicians (e.g., oncologists), mental health providers, supervised therapists-in-training (e.g., graduate students), or other related provider delivering the MCP-L experimental intervention
* Providing care (or services) to Mexican cancer patients at INCan
* Has access to internet and an electronic device
* Agrees to be audio-recorded

Exclusion Criteria:

EMR Criteria

* Prior Treatment

* Received psychological or psychiatric care at INCan in the last 3 months
* In the judgment of the treating physician, protocol investigators, and/or study staff, presence of cognitive impairment (e.g., delirium or dementia) sufficient to preclude meaningful informed consent and/or study participation
* Diagnosed with a serious psychiatric condition

Self-Report Criteria

* Received psychological or psychiatric care outside of INCan in the last 3 months
* Presence of suicide risk determined by the Columbia-Suicide Severity Rating Scale
* Too ill to participate determined by the question: "Do you feel too ill to participate because of communication problems, uncontrollable pain, or other symptoms that prevent you from participating?"

Provider Eligibility Criteria:

Inclusion Criteria Self-Report Criteria

* Age ≥ 18 years
* Able to read and communicate in Spanish determined by the question: "Can you read and communicate in Spanish? Yes/No"
* Professional role of administrators, clinicians (e.g., oncologists), mental health providers, supervised therapists-in-training (e.g., graduate students), or other related provider delivering the MCP-L experimental intervention
* Providing care (or services) to Mexican cancer patients at INCan
* Has access to internet and an electronic device
* Agrees to be audio-recorded

Study Plan

Experimental Intervention

EXPERIMENTAL

Meaning-Centered Psychotherapy for Latinos (MCP-L)

  • BEHAVIORAL:

    Meaning-Centered Psychotherapy for Latinos /MCP-L

    Description:

    MCP-L is a structured 7-session manualized intervention culturally adapted into Spanish for Latino participants diagnosed with advanced cancer, which utilizes a mixture of didactics, discussion and experiential exercises that focus on particular themes related to meaning and advanced cancer. It is 60-minute individual sessions delivered every week or intermittently (depending on participant preference) for up to approximately 3 months (in this time period) in the event of medical illness.

Control Intervention

NO_INTERVENTION

Cognitive Behavioral Therapy (CBT)

    Outcome Measures

    Primary Outcome Measures

    Change in clinical levels of anxiety and depression for participants participating in Meaning-Centered Psychotherapy for Latinos (MCP-L)

    Time Frame: 1 month

    Change in clinical levels of anxiety and depression for participants participating in Meaning-Centered Psychotherapy for Latinos (MCP-L)

    Time Frame: 3 months

    Timeline

    • Last Updated
      August 3, 2026
    • Start Date
      November 6, 2025
    • Today
      October 6, 2026
    • Completion Date ( Estimated )
      April 13, 2029

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