Improvements in Dynamic Contrast-Enhanced MR Angiography and Perfusion and Non-Contrast MRI

Clinicaltrials.gov ID: NCT06315595
db-list-check Status RECRUITING
b-loader Phase
b-people Age ≥ 18 Years
b-bullseye-arrow Enrollments 1000

Conditions

Prostate Neoplasm

Summary

This study evaluates if technical improvements in MRI can be used to provide improved performance contrast-enhanced MRI as used for angiography and perfusion as well as in non-contrast MRI.

Detailed Description

PRIMARY OBJECTIVE:

I. To study how a variety of technological approaches in MRI can be used to provide improved performance contrast-enhanced MR imaging as used for angiography and perfusion as well as in MR image acquisition without the use of contrast material.

OUTLINE: This is an observational study.

Participants undergo a non-contrast MRI on study and may optionally undergo a second non-contrast MRI on study. Participants may also undergo blood sample collection on study.

Locations

1 location Found with status Recruiting

Status

  • RECRUITING

Contact Person

  • Clinical Trials Referral Office
  • 855-776-0015

Principal Investigator

  • Stephen J. Riederer, PhD

Eligibility Criteria

Inclusion Criteria:

* Adults

Exclusion Criteria:

* Standard exclusion criteria for clinical MRI; e.g. cardiac pacemaker, claustrophobia, an implanted device that has been determined to be MR conditional at 1.5T but not at 3T, anticipated considerable susceptibility artifact from hip prosthesis, etc.

Study Plan

Observational

Participants undergo a non-contrast MRI on study and may optionally undergo a second non-contrast MRI on study. Participants may also undergo blood sample collection on study.

  • OTHER:

    Non-Interventional Study

    Description:

    Non-interventional study

Outcome Measures

Primary Outcome Measures

Improved performance in contrast-enhanced magnetic resonance imaging (MRI) as used for angiography and perfusion

Time Frame: Baseline (at enrollment); possible second scan at a later date

Timeline

  • Last Updated
    December 13, 2024
  • Start Date
    March 18, 2024
  • Today
    May 11, 2025
  • Completion Date ( Estimated )
    September 30, 2030

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